Article
Novel polymorphisms in human macrophage inflammatory protein-1 alpha (MIP-1alpha) gene.
Genes and immunity - 1 May 2001
Xin X, Nakamura K, Liu H, Nakayama E E, Goto M, Nagai Y, Kitamura Y, Shioda T, Iwamoto A
Abstract excerpt
Human macrophage inflammatory protein-1 alpha (MIP-1alpha) is a chemotactic cytokine, which binds to macrophages, T cells, and B cells affecting their activation. We found novel polymorphisms at four sites within MIP-1alpha gene in Japanese population: C to T in exon 2; A to G in intron 2; C to G and A to G in exon 3. They occurred on the same allele. Although MIP-1alpha effectively suppresses the replication of...
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