Article
The MCP-1 promoter -2518 polymorphism in Behcet's disease: correlation between allele types, MCP-1 production and clinical symptoms among Korean patients.
Autoimmunity - 1 Feb 2004
Cho Mi-La, Kim Ju-Young, Ko Hyeok-Jae, Kim Young-Hoon, Kim Wan-Uk, Cho Chul-Soo, Kim Ho-Youn, Hwang Sue-Yun
Abstract excerpt
OBJECTIVE: To compare the G vs. A variation at the MCP-1 promoter -2518 position among normal Koreans and Behcet patients, and to investigate possible association of this polymorphism with disease pathogenesis. METHODS: The allele type of -2518 polymorphism was determined by restriction fragment length polymorphism of Pvu II. The level of MCP-1 in serum and culture supernatent was measured by sandwich ELISA....
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