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Article

Structural alterations of transforming growth factor-beta receptor genes in human cervical carcinoma.

International journal of cancer - 2 Jul 1999

Chen T, de Vries E G, Hollema H, Yegen H A, Vellucci V F, Strickler H D, Hildesheim A, Reiss M

Abstract excerpt

The development and progression of invasive uterine cervical carcinomas appear to be associated with the progressive loss of sensitivity to transforming growth factor-beta (TGFbeta)-mediated cell cycle arrest. In order to identify possible molecular mechanisms responsible for TGFbeta resistance, we screened the 7 exons of the type II (TbetaR-II) TGFbeta receptor and the 9 exons of the type I (TbetaR-I) TGFbeta...

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Identifiers

PMID: 10360819
DOI: 10.1002/(sici)1097-0215(19990702)82:1<43::aid-ijc9>3.0.co;2-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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