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Article

Changes in expression, and/or mutations in TGF-beta receptors (TGF-beta RI and TGF-beta RII) and Smad 4 in human ovarian tumors.

Journal of cancer research and clinical oncology - 1 Mar 2010

Antony Marie Lue, Nair Rema, Sebastian Paul, Karunagaran Devarajan

Abstract excerpt

PURPOSE: Loss of sensitivity to transforming growth factor beta (TGF-beta) signaling typically occurs in human ovarian cancer cells, but there is paucity of information regarding this in human ovarian tumors. Thus the association of inactivating mutations and/or variations in expression levels of TGF-beta signaling components with human ovarian tumors was evaluated. METHODS: Forty human ovarian tissue samples...

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Source

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PMID: 19916025
DOI: 10.1007/s00432-009-0703-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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