Decreased expression of TGF-beta cell surface receptors during progression of human oral squamous cell carcinoma.

doi:10.1002/1096-9896(2000)9999:9999<::AID-PATH822>3.0.CO;2-V

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Article

Decreased expression of TGF-beta cell surface receptors during progression of human oral squamous cell carcinoma.

The Journal of pathology - 1 Apr 2001

Paterson I C, Matthews J B, Huntley S, Robinson C M, Fahey M, Parkinson E K, Prime S S

Abstract excerpt

This study examined the immunocytochemical expression of the transforming growth factor-beta (TGF-beta) isoforms TGF-beta1, TGF-beta2, and TGF-beta3, together with the TGF-beta cell surface receptors TbetaR-I and TbetaR-II, in patient-matched tissue pairs of normal human oral epithelium, primary squamous cell carcinomas, and metastatic lymph node tumour deposits. There were no significant differences in the...

Topics

Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell
Disease Progression
Female
Humans
Immunoenzyme Techniques
Lymphatic Metastasis
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mouth Neoplasms

Mutation

Neoplasm Proteins

Protein Isoforms

Receptors, Transforming Growth Factor beta

Transforming Growth Factor beta

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 11276004
DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH822>3.0.CO;2-V

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