Article
RhD status of a fetus at risk for haemolytic disease with a discrepant maternal DNA-based RhD genotype.
Prenatal diagnosis - 1 May 1999
Denomme G A, Akoury H, Sermer M, Kelton J G
Abstract excerpt
The cloning of the RHD gene has made it possible to determine the RhD status of fetuses at risk for haemolytic disease due to RhD iso-immunization using amniotic fluid or chorionic villi-derived DNA and the polymerase chain reaction. However, some Rh haplotypes are associated with false-positive or negative DNA-based results with the potential for an adverse outcome. We determined the RhD status of a fetus using...
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