Article
[RHD variant in RhD/-/ mother with anti-D makes noninvasive fetal RHD genotyping impossible].
Ginekologia polska - 1 Oct 2009
Orzińska Agnieszka, Engel Karina, Łakomy Magdalena, Smolarczyk-Wodzyńska Justyna, Lipińska Anna, Pelc-Kłopotowska Monika, Brojer Ewa
Abstract excerpt
OBJECTIVES: Noninvasive fetal RHD genotyping from maternal plasma of RhD(/-) pregnant women of Caucasian race may be used for predicting the risk of hemolytic disease because the RHD gene is usually absent in such populations. If detected in plasma of such women, the RHD gene originates from the RhD(+) fetus. The number of fetal copies of the gene in maternal plasma is extremely small. In the presented case of...
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