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Article

Frequency and characterization of known and novel RHD variant alleles in 37 782 Dutch D-negative pregnant women.

British journal of haematology - 1 May 2016

Stegmann Tamara C, Veldhuisen Barbera, Bijman Renate, Thurik Florentine F, Bossers Bernadette, Cheroutre Goedele, Jonkers Remco, Ligthart Peter, de Haas Masja, Haer-Wigman Lonneke, van der Schoot C Ellen

Abstract excerpt

To guide anti-D prophylaxis, Dutch D- pregnant women are offered a quantitative fetal-RHD-genotyping assay to determine the RHD status of their fetus. This allowed us to determine the frequency of different maternal RHD variants in 37 782 serologically D- pregnant women. A variant allele is present in at least 0·96% of Dutch D- pregnant women The D- serology could be confirmed after further serological testing in...

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Identifiers

PMID: 27018217
DOI: 10.1111/bjh.13960

Genes

RHD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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