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Article

A generalized family-based association test for dichotomous traits.

American journal of human genetics - 1 Sept 2009

Chen Wei-Min, Manichaikul Ani, Rich Stephen S

Abstract excerpt

Recent advances in genotyping technology make it possible to utilize large-scale association analysis for disease-gene mapping. Powerful and robust family-based association methods are crucial for successful gene mapping. We propose a family-based association method, the generalized disequilibrium test (GDT), in which the genotype differences of all discordant relative pairs are utilized in assessing association...

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Identifiers

PMID: 19732865
DOI: 10.1016/j.ajhg.2009.08.003
PMCID: PMC2771538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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