Sex differences in supraspinal morphine analgesia are dependent on genotype.

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Article

Sex differences in supraspinal morphine analgesia are dependent on genotype.

The Journal of pharmacology and experimental therapeutics - 1 Jun 1999

Kest B, Wilson S G, Mogil J S

Abstract excerpt

Several variables have been reported to affect the expression of sex differences in the analgesic potency of morphine. Although the effect of genetic background on morphine analgesia has been well documented, the relevance of genotype to sex differences in morphine analgesia has rarely been considered. The present study investigated morphine dose-response relationships in male and female mice of 11 inbred mouse...

Topics

Analgesia
Animals
Cerebral Ventricles
Dose-Response Relationship, Drug
Female
Genotype
Injections, Intraventricular
Male
Mice
Mice, Inbred A
Mice, Inbred AKR
Mice, Inbred BALB C
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Inbred CBA
Mice, Inbred Strains
Morphine
Sex Characteristics

Source

Open in PubMed

Identifiers

PMID: 10336528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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