Article
Sex and genotype determine the selective activation of neurochemically-distinct mechanisms of swim stress-induced analgesia.
Pharmacology, biochemistry, and behavior - 1 Jan 1997
Mogil J S, Belknap J K
Abstract excerpt
A growing literature documents the important influence of organismic factors such as sex and genotype on pain sensitivity and pain modulation. We recently determined that 3-min forced swims in 15 degrees C water produce non-opioid (i.e., naloxone-insensitive) analgesia in outbred Swiss-Webster mi...
Topics
- Analgesia
- Animals
- Brain Chemistry
- Dizocilpine Maleate
- Excitatory Amino Acid Antagonists
- Female
- Genotype
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Naloxone
- Narcotic Antagonists
- Pain Measurement
- Reaction Time
- Sex Characteristics
- Species Specificity
- Stress, Psychological
