Article
Motivational effects of opiates in conditioned place preference and aversion paradigm--a study in three inbred strains of mice.
Psychopharmacology - 1 Dec 2009
Solecki Wojciech, Turek Anna, Kubik Jakub, Przewlocki Ryszard
Abstract excerpt
RATIONALE: Interstrain differences in the motivational properties of morphine and heroin have been previously reported in mice, suggesting the involvement of a genotype-dependent modulation of the rewarding effects of opiates. Yet, interstrain differences in the motivational effects of naloxone have not been described. OBJECTIVES: The aim of our study was to examine genotype modulation of the motivational effects...
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