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Article

Expression of aberrant functional and nonfunctional transcripts of the FHIT gene in Burkitt's lymphomas.

Molecular carcinogenesis - 1 May 1999

Ferrer M, López-Borges S, Lazo P A

Abstract excerpt

The 3p14.2 chromosome region, which contains the FHIT gene and the FRA3B fragile site, is frequently altered in carcinomas. We analyzed the expression of the FHIT gene in 21 Burkitt's lymphoma cell lines and normal lymphoid populations. Seventeen (80%) of these cell lines had a common aberrant FHIT transcript as well as the normal transcript. Exon 2 was often aberrantly spliced to several coding exons, skipping...

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Source

Identifiers

PMID: 10331745
DOI: 10.1002/(sici)1098-2744(199905)25:1<55::aid-mc7>3.0.co;2-3

Genes

FHIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression of aberrant functional and nonfunctional transcripts of the FHIT gene in Burkitt's lymphomas.PMID 10331745Read ↗

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