Article
Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets.
Genes & development - 1 May 1999
Kaiser P, Moncollin V, Clarke D J, Watson M H, Bertolaet B L, Reed S I, Bailly E
Abstract excerpt
Cell cycle-specific proteolysis is critical for proper execution of mitosis in all eukaryotes. Ubiquitination and subsequent proteolysis of the mitotic regulators Clb2 and Pds1 depend on the cyclosome/APC and the 26S proteasome. We report here that components of the cell cycle machinery in yeast,...
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