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Article

Drosophila Cks30A interacts with Cdk1 to target Cyclin A for destruction in the female germline.

Development (Cambridge, England) - 1 Aug 2005

Swan Andrew, Barcelo Gail, Schüpbach Trudi

Abstract excerpt

Cks is a small highly conserved protein that plays an important role in cell cycle control in different eukaryotes. Cks proteins have been implicated in entry into and exit from mitosis, by promoting Cyclin-dependent kinase (Cdk) activity on mitotic substrates. In yeast, Cks can promote exit from mitosis by transcriptional regulation of cell cycle regulators. Cks proteins have also been found to promote S-phase...

Topics

Amino Acid Sequence
Animals
CDC2 Protein Kinase
Cyclin A
Cyclin-Dependent Kinases
Drosophila Proteins
Drosophila melanogaster
Female
Germ Cells
Humans
In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Meiosis

Molecular Sequence Data

Phenotype

Phylogeny

Sequence Alignment

Source

Identifiers

PMID: 16033797
DOI: 10.1242/dev.01940

Genes

CDC20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Click a neighbor to travelStep 1 · 12 closest

Drosophila Cks30A interacts with Cdk1 to target Cyclin A for destruction in the female germline.PMID 16033797Read ↗

Requirement of Cks2 for the first metaphase/anaphase transition of mammalian meiosis.Semantic proximity Read ↗

Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets.Semantic proximity Read ↗

Cyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells.Semantic proximity Read ↗

Cyclin B3 promotes APC/C activation and anaphase I onset in oocyte meiosisSemantic proximity Read ↗

C. elegans RBX-2-CUL-5- and RBX-1-CUL-2-based complexes are redundant for oogenesis and activation of the MAP kinase MPK-1.Semantic proximity Read ↗

Drosophila skpA, a component of SCF ubiquitin ligases, regulates centrosome duplication independently of cyclin E accumulation.Semantic proximity Read ↗

Cyclin B3 promotes anaphase I onset in oocyte meiosisSemantic proximity Read ↗

The Cdk-activating kinase Cak1p promotes meiotic S phase through Ime2p.Semantic proximity Read ↗

Fbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5.Semantic proximity Read ↗

Anaphase onset requires CKS-1-mediated destruction of securin in meiosis I and cyclin B1 in meiosis II.Semantic proximity Read ↗

Cdc20 hypomorphic mice fail to counteract de novo synthesis of cyclin B1 in mitosis.Semantic proximity Read ↗

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box.Semantic proximity Read ↗

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