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Article

Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 May 1999

Xie W F, Zhang X, Sakano S, Lefebvre V, Sandell L J

Abstract excerpt

The transcription factor Sox9 is capable of enhancing type II collagen gene expression and may play a crucial role in chondrogenesis. To determine whether Sox9 is an inducer of the chondrocyte phenotype, we investigated the role of Sox9 in transcription of another cartilage gene encoding the cartilage-derived retinoic acid-sensitive protein (CD-RAP). CD-RAP is specifically expressed during chondrogenesis. We show...

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Share to Cartilage
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extracellular Matrix Proteins

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Share to Sex-Determining Region Y Protein

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Source

Identifiers

PMID: 10320524
DOI: 10.1359/jbmr.1999.14.5.757

Genes

SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9.PMID 10320524Read ↗

Sox9 is required for cartilage formation.Semantic proximity Read ↗

SOX9 Exerts a Bifunctional Effect on Type II Collagen Gene (COL2A1) Expression in Chondrocytes Depending on the Differentiation StateSemantic proximity Read ↗

SOX9 and the many facets of its regulation in the chondrocyte lineageSemantic proximity Read ↗

Regulation of Cartilage Development and Diseases by Transcription FactorsSemantic proximity Read ↗

SOX9-dependent and -independent Transcriptional Regulation of Human Cartilage Link ProteinSemantic proximity Read ↗

The postnatal role of Sox9 in cartilage.Semantic proximity Read ↗

Cloning of a Retinoic Acid-sensitive mRNA Expressed in Cartilage and during ChondrogenesisSemantic proximity Read ↗

Sox9-dependent transcriptional regulation of the proprotein convertase furin.Semantic proximity Read ↗

Potent Inhibition of the Master Chondrogenic FactorSox9 Gene by Interleukin-1 and Tumor Necrosis Factor-αSemantic proximity Read ↗

Transcriptional coactivator PGC-1α regulates chondrogenesis via association with Sox9Semantic proximity Read ↗

Transcriptional mechanisms of chondrocyte differentiation.Semantic proximity Read ↗

Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9Semantic proximity Read ↗

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