Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sox9-dependent transcriptional regulation of the proprotein convertase furin.

American journal of physiology. Cell physiology - 1 Jul 2007

Guimont Philippe, Grondin Francine, Dubois Claire M

Abstract excerpt

The proprotein convertase furin participates in the maturation/bioactivation of a variety of proproteins involved in chondrogenesis events. These include parathyroid hormone-related peptide (PTHrP), an autocrine/paracrine factor that is crucial to both normal cartilage development and cartilage-related pathological processes. Despite the known importance of furin activity in the bioactivation of the polypeptides,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chondrocytes
Share to Chondrogenesis
Share to Furin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High Mobility Group Proteins

Share to Luciferases

Share to Parathyroid Hormone-Related Protein

Share to SOX9 Transcription Factor

Share to SOXD Transcription Factors

Source

Identifiers

PMID: 17360815
DOI: 10.1152/ajpcell.00349.2006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sox9-dependent transcriptional regulation of the proprotein convertase furin.PMID 17360815Read ↗

Regulation of Cartilage Development and Diseases by Transcription FactorsSemantic proximity Read ↗

Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9Semantic proximity Read ↗

SOX9 and the many facets of its regulation in the chondrocyte lineageSemantic proximity Read ↗

Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian ChondrocyteSemantic proximity Read ↗

L-Sox5 and Sox6 Proteins Enhance Chondrogenic miR-140 MicroRNA Expression by Strengthening Dimeric Sox9 ActivitySemantic proximity Read ↗

Transcriptional mechanisms of chondrocyte differentiation.Semantic proximity Read ↗

SOX9: a key transcriptional regulator in organ fibrosisSemantic proximity Read ↗

Brief Report: Importance of SOX8 for In Vitro Chondrogenic Differentiation of Human Mesenchymal Stromal CellsSemantic proximity Read ↗

SOX9 in organogenesis: shared and unique transcriptional functions.Semantic proximity Read ↗

SOX9-dependent and -independent Transcriptional Regulation of Human Cartilage Link ProteinSemantic proximity Read ↗

The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9.Semantic proximity Read ↗

Evolutionarily conserved, growth plate zone-specific regulation of the matrilin-1 promoter: L-Sox5/Sox6 and Nfi factors bound near TATA finely tune activation by Sox9.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.