Article
Cloning of a Retinoic Acid-sensitive mRNA Expressed in Cartilage and during Chondrogenesis
1 Feb 1996
Abstract excerpt
Retinoic acid (RA) is known to play a role in various aspects of skeletal development in vivo, including morphogenesis, growth plate maturation, and apoptosis. In cell culture, RA treatment of chondrocytes suppresses the differentiated phenotype characterized by production of type II collagen and aggrecan. In an effort to discover molecules involved in regulation of the chondrocyte phenotype or related to...
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