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Article

Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9

11 Aug 2015

Abstract excerpt

RBPjk-dependent Notch signaling regulates both the onset of chondrocyte hypertrophy and the progression to terminal chondrocyte maturation during endochondral ossification. It has been suggested that Notch signaling can regulate Sox9 transcription, although how this occurs at the molecular level in chondrocytes and whether this transcriptional regulation mediates Notch control of chondrocyte hypertrophy and...

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Identifiers

PMID: 26558140
DOI: 10.1038/boneres.2015.21

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