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Article

Regulation of Cartilage Development and Diseases by Transcription Factors

1 Jan 2017

Abstract excerpt

Genetic studies and molecular cloning approaches have been successfully used to identify several transcription factors that regulate the numerous stages of cartilage development. Sex-determining region Y (SRY)-box 9 (Sox9) is an essential transcription factor for the initial stage of cartilage development. Sox5 and Sox6 play an important role in the chondrogenic action of Sox9, presumably by defining its...

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PMID: 28955690
DOI: 10.11005/jbm.2017.24.3.147

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