A mutation affecting carbon catabolite repression suppresses growth defects in pyruvate carboxylase mutants from Saccharomyces cerevisiae.

doi:10.1016/0014-5793(95)01337-7

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Article

A mutation affecting carbon catabolite repression suppresses growth defects in pyruvate carboxylase mutants from Saccharomyces cerevisiae.

FEBS letters - 18 Dec 1995

Blázquez M A, Gamo F J, Gancedo C

Abstract excerpt

Yeasts with disruptions in the genes PYC1 and PYC2 encoding the isoenzymes of pyruvate carboxylase cannot grow in a glucose-ammonium medium (Stucka et al. (1991) Mol. Gen. Genet. 229, 307-315). We have isolated a dominant mutation, BPC1-1, that allows growth in this medium of yeasts with interrup...

Topics

Alleles
Base Sequence
Carbon
Culture Media
DNA, Fungal
Glucose
Glyoxylates
Isoenzymes
Molecular Sequence Data
Mutation
Phenotype
Pyruvate Carboxylase
Quaternary Ammonium Compounds
Saccharomyces cerevisiae

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