Article
Acidic fibroblast growth factor induces an antifibrogenic phenotype in human lung fibroblasts.
American journal of respiratory cell and molecular biology - 1 May 1999
Becerril C, Pardo A, Montaño M, Ramos C, Ramírez R, Selman M
Abstract excerpt
Acidic fibroblast growth factor (FGF-1), a prototype member of the heparin-binding growth factor family, influences proliferation, differentiation, and protein synthesis in different cell types. However, its possible role on lung extracellular matrix (ECM) metabolism has not been evaluated. In this study we examined the effects of FGF-1 and FGF-1 plus heparin on type I collagen, collagen-binding stress protein...
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