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Article

Fluorescent Chloride Indicators to Assess the Efficacy of CFTR cDNA Delivery

10 Apr 1999

Abstract excerpt

Cl(-)-sensitive fluorescent indicators have been used extensively in cell culture systems to measure the Cl(-)-transporting function of the cystic fibrosis transmembrane conductance regulator protein CFTR. These indicators have been used in establishing a surrogate end point to assess the efficacy of CFTR cDNA delivery in human gene therapy trials. The ability to measure Cl- transport with high sensitivity in...

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Share to Advanced biosensing and bioanalysis techniques
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Identifiers

PMID: 10223721
DOI: 10.1089/10430349950018274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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