Article

A carbon nanotube optical reporter maps endolysosomal lipid flux

2017-05-06

Abstract excerpt

<h4>ABSTRACT</h4> Lipid accumulation within the lumen of endolysosomal vesicles is observed in various pathologies including atherosclerosis, liver disease, neurological disorders, lysosomal storage disorders, and cancer. Current methods cannot measure lipid flux specifically within the lysosomal lumen of live cells. We developed an optical reporter, composed of a photoluminescent carbon nanotube of a single chir...

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Identifiers and source

Literature Corpus work: 3b793691-eb01-5fef-b7f5-a507e93d62bf
DOI: 10.1101/134999

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