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Article

Simple image-based no-wash method for quantitative detection of surface expressed CFTR.

Methods (San Diego, Calif.) - 1 Mar 2016

Larsen Mads Breum, Hu Jennifer, Frizzell Raymond A, Watkins Simon C

Abstract excerpt

Cystic fibrosis (CF) is the most common lethal genetic disease among Caucasians. It is caused by mutations in the CF Transmembrane Conductance Regulator (CFTR) gene, which encodes an apical membrane anion channel that is required for regulating the volume and composition of epithelial secretions. The most common CFTR mutation, present on at least one allele in >90% of CF patients, deletes phenylalanine at...

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Source

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Identifiers

PMID: 26361332
DOI: 10.1016/j.ymeth.2015.09.006
PMCID: PMC4773656

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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