Article
Differential chromosome allelic imbalance in the progression of human prostate cancer.
The Journal of urology - 1 Dec 1996
Latil A, Fournier G, Cussenot O, Lidereau R
Abstract excerpt
PURPOSE: It is widely accepted that an accumulation of genetic alterations plays an important role in the genesis of human cancers. We wished to obtain a comprehensive view of the role of genetic changes in prostate cancer. MATERIALS AND METHODS: We screened 42 primary prostate tumors for allelic imbalance (AI) on 8 autosomal chromosome arms of interest (5q, 7q, 8p, 10q, 13q, 16q, 17q, 18q) by using 2 DNA probes...
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