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Article

Allelic loss in locally metastatic, multisampled prostate cancer.

Cancer research - 15 Jun 1994

Sakr W A, Macoska J A, Benson P, Grignon D J, Wolman S R, Pontes J E, Crissman J D

Abstract excerpt

In order to determine whether retention or loss of potential tumor suppressor loci that map to 8p, 10q, or 16q reflect genetic relationships among prostatic intraepithelial neoplasias (PINs), multicentric primary prostatic cancers, and regional lymph node metastases or are associated with the metastatic phenotype, we analyzed 19 cases of locally metastatic prostate carcinoma (stage D1) utilizing polymerase chain...

Topics

Alleles
Base Sequence
Chromosomes, Human, Pair 10
Chromosomes, Human, Pair 16
Chromosomes, Human, Pair 8
Gene Deletion
Genetic Markers
Humans
Male
Molecular Sequence Data
Neoplasm Metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Predictive Value of Tests

Prognosis

Prostatic Hyperplasia

Prostatic Neoplasms

Source

Identifiers

PMID: 7515768

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7515768-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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