Article
Allelic loss in locally metastatic, multisampled prostate cancer.
Cancer research - 15 Jun 1994
Sakr W A, Macoska J A, Benson P, Grignon D J, Wolman S R, Pontes J E, Crissman J D
Abstract excerpt
In order to determine whether retention or loss of potential tumor suppressor loci that map to 8p, 10q, or 16q reflect genetic relationships among prostatic intraepithelial neoplasias (PINs), multicentric primary prostatic cancers, and regional lymph node metastases or are associated with the metastatic phenotype, we analyzed 19 cases of locally metastatic prostate carcinoma (stage D1) utilizing polymerase chain...
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