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Article

Independent origin of multiple foci of prostatic intraepithelial neoplasia: comparison with matched foci of prostate carcinoma.

Cancer - 1 Nov 1998

Bostwick D G, Shan A, Qian J, Darson M, Maihle N J, Jenkins R B, Cheng L

Abstract excerpt

BACKGROUND: Prostate carcinoma usually is heterogeneous and multifocal, with diverse clinical and morphologic manifestations. Understanding of the molecular basis for this heterogeneity is limited, particularly for the putative precursor, high grade prostatic intraepithelial neoplasia (PIN). In this study, the authors attempted to determine the genetic relation between multiple foci of PIN and matched foci of...

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PMID: 9806659
DOI: 10.1002/(sici)1097-0142(19981101)83:9<1995::aid-cncr16>3.0.co;2-2

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