Independent origin of multiple foci of prostatic intraepithelial neoplasia: comparison with matched foci of prostate carcinoma.

doi:10.1002/(sici)1097-0142(19981101)83:9<1995::aid-cncr16>3.0.co;2-2

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Article

Independent origin of multiple foci of prostatic intraepithelial neoplasia: comparison with matched foci of prostate carcinoma.

Cancer - 1 Nov 1998

Bostwick D G, Shan A, Qian J, Darson M, Maihle N J, Jenkins R B, Cheng L

Abstract excerpt

BACKGROUND: Prostate carcinoma usually is heterogeneous and multifocal, with diverse clinical and morphologic manifestations. Understanding of the molecular basis for this heterogeneity is limited, particularly for the putative precursor, high grade prostatic intraepithelial neoplasia (PIN). In t...

Topics

Aged
Alleles
Carcinoma
Genetic Heterogeneity
Humans
Male
Middle Aged
Neoplasm Staging
Prostatic Neoplasms

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