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Article

Reversible tumorigenesis induced by deficiency of vasodilator-stimulated phosphoprotein.

Molecular and cellular biology - 1 May 1999

Liu K, Li L, Nisson P E, Gruber C, Jessee J, Cohen S N

Abstract excerpt

Random homozygous knockout (RHKO) is an antisense RNA strategy capable of identifying genes whose homozygous functional inactivation yields a selectable phenotype in cells growing in culture. Using this approach, we isolated NIH 3T3 fibroblast clones that showed the ability to form colonies on 0.5% agar and tumors in nude mice. The gene inactivated in one of these clones was found to encode VASP...

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Share to 3T3 Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Nude

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Share to RNA, Antisense

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Source

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Identifiers

PMID: 10207093
DOI: 10.1128/MCB.19.5.3696
PMCID: PMC84183

Genes

VASP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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