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Article

High-Throughput RNAi Screening Identifies a Role for the Osteopontin Pathway in Proliferation and Migration of Human Aortic Smooth Muscle Cells.

Cardiovascular drugs and therapy - 1 Jun 2016

Zhang Lei, Erfle Holger, Harder Nathalie, Beneke Jürgen, Beil Nina, Bulkescher Ruben, Rohr Karl, Keese Michael

Abstract excerpt

PURPOSE: Understanding of the mechanisms of vascular smooth muscle cells (VSMCs) phenotypic regulation is critically important to identify novel candidates for future therapeutic intervention. While HTS approaches have recently been used to identify novel regulators in many cell lines, such as cancer cells and hematopoietic stem cells, no studies have so far systematically investigated the effect of gene...

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Identifiers

PMID: 27095116
DOI: 10.1007/s10557-016-6663-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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