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Article

Yeast mutants affecting possible quality control of plasma membrane proteins.

Molecular and cellular biology - 1 May 1999

Li Y, Kane T, Tipper C, Spatrick P, Jenness D D

Abstract excerpt

Mutations gef1, stp22, STP26, and STP27 in Saccharomyces cerevisiae were identified as suppressors of the temperature-sensitive alpha-factor receptor (mutation ste2-3) and arginine permease (mutation can1(ts)). These suppressors inhibited the elimination of misfolded receptors (synthesized at 34 degrees C) as well as damaged surface receptors (shifted from 22 to 34 degrees C). The stp22 mutation (allelic to vps23...

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Identifiers

PMID: 10207082
DOI: 10.1128/MCB.19.5.3588
PMCID: PMC84152

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