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Article

New mutants of Saccharomyces cerevisiae affected in the transport of proteins from the endoplasmic reticulum to the Golgi complex.

Genetics - 1 Feb 1996

Wuestehube L J, Duden R, Eun A, Hamamoto S, Korn P, Ram R, Schekman R

Abstract excerpt

We have isolated new temperature-sensitive mutations in five complementation groups, sec31-sec35, that are defective in the transport of proteins from the endoplasmic reticulum (ER) to the Golgi complex. The sec31-sec35 mutants and additional alleles of previously identified sec and vacuolar protein sorting (vps) genes were isolated in a screen based on the detection of alpha-factor precursor in yeast colonies...

Topics

Biological Transport
Endoplasmic Reticulum
Epistasis, Genetic
Fungal Proteins
Gene Expression Regulation, Fungal
Golgi Apparatus
Immunoblotting
Membrane Proteins
Mutation
Protein Precursors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

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Identifiers

PMID: 8852839
DOI: 10.1093/genetics/142.2.393
PMCID: PMC1206974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8852839-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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New mutants of Saccharomyces cerevisiae affected in the transport of proteins from the endoplasmic reticulum to the Golgi complex.PMID 8852839Read ↗

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