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Article

Plasma membrane microdomains regulate turnover of transport proteins in yeast.

The Journal of cell biology - 15 Dec 2008

Grossmann Guido, Malinsky Jan, Stahlschmidt Wiebke, Loibl Martin, Weig-Meckl Ina, Frommer Wolf B, Opekarová Miroslava, Tanner Widmar

Abstract excerpt

In this study, we investigate whether the stable segregation of proteins and lipids within the yeast plasma membrane serves a particular biological function. We show that 21 proteins cluster within or associate with the ergosterol-rich membrane compartment of Can1 (MCC). However, proteins of the endocytic machinery are excluded from MCC. In a screen, we identified 28 genes affecting MCC appearance and found that...

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Identifiers

PMID: 19064668
DOI: 10.1083/jcb.200806035
PMCID: PMC2600745

Genes

MCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Plasma membrane microdomains regulate turnover of transport proteins in yeast.PMID 19064668Read ↗

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