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Article

Three measures of mutagen sensitivity in a cancer-free population.

Cancer genetics and cytogenetics - 1 Apr 1999

Gu J, Bondy M L, Sigurdson A, Spitz M R, Hsu T C, Wu X

Abstract excerpt

Different individuals appear to respond differently to the same carcinogen, and different mutagens act differently on cells. We conducted mutagen sensitivity assays by using three mutagens (bleomycin, a radiomimetic agent; 4-nitroquinoline-1-oxide [4-NQO], an ultraviolet light mimetic agent; and benzo[a]pyrene diol epoxide [BPDE], a tobacco mutagen) in parallel in healthy human subjects to determine the...

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PMID: 10198626
DOI: 10.1016/s0165-4608(98)00189-7

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