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Article

Correlates of mutagen sensitivity in patients with upper aerodigestive tract cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 1997

Spitz M R, McPherson R S, Jiang H, Hsu T C, Trizna Z, Lee J J, Lippman S M, Khuri F R, Steffen-Batey L, Chamberlain R M, Schantz S P, Hong W K

Abstract excerpt

Although tobacco and alcohol use are the major determinants of upper aerodigestive tract carcinogenesis, not all smokers develop cancer. This phenomenon is due to individual variation in genetic susceptibility to carcinogens. One explanation may be differences in mutagen sensitivity (as measured...

Topics

Adult
Aged
Alcohol Drinking
Antineoplastic Agents
Antioxidants
Carcinoma, Squamous Cell
Diet
Female
Genetic Predisposition to Disease
Head and Neck Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Logistic Models

Male

Middle Aged

Mutagenesis

Mutagenicity Tests

Neoplasms, Second Primary

Risk Factors

Source

Identifiers

PMID: 9298575

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9298575-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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