Article
Asynchronous replication of alleles in genomes carrying an extra autosome.
European journal of human genetics : EJHG - 1 Jan 2000
Amiel A, Korenstein A, Gaber E, Avivi L
Abstract excerpt
Transcriptional activity of genes appears to be highly related to their replication timing; alleles showing the common biallelic mode of expression replicate highly synchronously, whereas those with a monoallelic mode of expression replicate asynchronously. Here we used FISH to determine the level of synchronisation in replication timing of alleles in amniotic fluid cells derived from normal foetuses and from...
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