Article
fcsA29 mutation is an allele of polA gene of Escherichia coli.
Bioscience, biotechnology, and biochemistry - 1 Feb 1999
Nagano K, Wachi M, Takada A, Takaku F, Hirasawa T, Nagai K
Abstract excerpt
The cold-sensitive fcsA29 mutation of Escherichia coli was found to be a new type of cold-sensitive allele of the polA gene encoding DNA polymerase I, caused by an Asp(116)-->Asn change in the 5'-->3' exonuclease domain. The fcsA29 mutant showed typical polA mutant phenotypes such as UV sensitivity and unacceptability of recA mutation. Cold-sensitive growth of the mutant was suppressed by introduction of a sulA...
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