Article
Characterization and purification of carbohydrate response element-binding protein of the rat L-type pyruvate kinase gene promoter.
Biochemical and biophysical research communications - 2 Apr 1999
Yamada K, Tanaka T, Noguchi T
Abstract excerpt
The L-III transcriptional regulatory element of the rat pyruvate kinase L gene is located between -170 and -150 base pairs upstream of the hepatocyte-specific transcription initiation site. As the L-III element is not only necessary for cell type-specific expression but also for transcriptional stimulation by carbohydrates, it is also referred to as a carbohydrate-response element. Electrophoretic mobility shift...
Topics
- Adenoviridae
- Animals
- Carbohydrates
- Cell Nucleus
- DNA-Binding Proteins
- Gene Expression Regulation
- Hot Temperature
- Humans
- Immune Sera
- Liver
- Male
- Molecular Weight
- Mutation
- Oligonucleotides
- Promoter Regions, Genetic
- Protein Binding
- Pyruvate Kinase
- Rats