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Article

Characterization of the human liver fructose-1,6-bisphosphatase gene promoter.

The Biochemical journal - 15 Oct 2000

Herzog B, Waltner-Law M, Scott D K, Eschrich K, Granner D K

Abstract excerpt

Fructose-1,6-bisphosphatase (FBPase; EC 3.1.3.11), an important gluconeogenic enzyme, catalyses the hydrolysis of fructose 1, 6-bisphosphate to fructose 6-phosphate and P(i). Enzyme activity is mainly regulated by the allosteric inhibitors fructose 2, 6-bisphosphate and AMP. Although some observations about hormonal regulation of the enzyme have been published, the FBPase promoter has not been studied in detail....

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Identifiers

PMID: 11023824
PMCID: PMC1221374

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