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Article

Identification of core sequences involved in metabolism-dependent nuclear protein binding to the rat insulin-like growth factor I gene.

Endocrinology - 1 Oct 1999

Zhu J L, Pao C I, Hunter E, Lin K W, Wu G J, Phillips L S

Abstract excerpt

In the liver, most insulin-like growth factor I (IGF-I) transcripts originate in exon 1, where important cis-regulatory regions are located downstream from the major transcription initiation sites. Within these regions, we have attempted to identify sequences which are involved in the decrease in IGF-I gene transcription associated with diabetes mellitus. The function of different genomic templates was assessed...

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PMID: 10499536
DOI: 10.1210/endo.140.10.7098

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EBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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