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Article

Differential regulation of the clusterin gene by Ha-ras and c-myc oncogenes and during apoptosis.

Journal of cellular physiology - 1 Dec 1998

Klock G, Storch S, Rickert J, Gutacker C, Koch-Brandt C

Abstract excerpt

Clusterin (ApoJ) is an extracellular glycoprotein expressed during processes of tissue differentiation and regression that involve programmed cell death (apoptosis). Increased clusterin expression has also been found in tumors, however, the mechanism underlying this induction is not known. Apoptotic processes in tumors could be responsible for clusterin gene activation. Alternatively, oncogenic mutations could...

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Identifiers

PMID: 10092212
DOI: 10.1002/(SICI)1097-4652(199812)177:4<593::AID-JCP10>3.0.CO;2-F

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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