Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of c-myc-transformed rat fibroblasts resistant to apoptosis induced ny growth factor deprivation.

Experimental cell research - 10 Apr 1996

Dhanaraj S N, Marcus A M, Korah R M, Iwata K, Small M B

Abstract excerpt

Under appropriate conditions (e.g., growth factor withdrawal), the deregulated expression of c-myc in rodent fibroblasts leads to substantial cell death due to apoptosis. To better understand this process, we selected for c-myc-transformed Rat1A fibroblasts that were resistant to growth factor deprivation-induced cell death. One clonal isolate exhibited prolonged survival in serum-free medium and displayed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Cell Division
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cells, Cultured

Share to Fibroblasts

Share to Phenotype

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 8612691
DOI: 10.1006/excr.1996.0110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of c-myc-transformed rat fibroblasts resistant to apoptosis induced ny growth factor deprivation.PMID 8612691Read ↗

Transformed Cells Require Continuous Activity Of RNA Polymerase II To Resist Oncogene-Induced ApoptosisSemantic proximity Read ↗

Targeting of Miz-1 is essential for Myc-mediated apoptosis.Semantic proximity Read ↗

Human c-Myc isoforms differentially regulate cell growth and apoptosis in Drosophila melanogaster.Semantic proximity Read ↗

Mammalian cells resistant to tumor suppressor genes.Semantic proximity Read ↗

c-myc box II mutations in Burkitt's lymphoma-derived alleles reduce cell-transformation activity and lower response to broad apoptotic stimuli.Semantic proximity Read ↗

The heparin-binding domain and V region of fibronectin regulate apoptosis by suppression of p53 and c-myc in human primary cells.Semantic proximity Read ↗

Induction of apoptosis by the c-Myc helix-loop-helix/leucine zipper domain in mouse 3T3-L1 fibroblasts.Semantic proximity Read ↗

Induction of cell cycle progression and acceleration of apoptosis are two separable functions of c-Myc: transrepression correlates with acceleration of apoptosis.Semantic proximity Read ↗

Differential sensitivity of murine myeloid FDC-P1 cells and apoptosis resistant mutant(s) to anticancer drugs.Semantic proximity Read ↗

Apoptosis-prone phenotype of human colon carcinoma cells with a high level amplification of the c-myc gene.Semantic proximity Read ↗

Fas-independent apoptosis in T-cell tumours induced by the CD2-myc transgene.Semantic proximity Read ↗

Somatic cell mutants resistant to retrovirus replication: intracellular blocks during the early stages of infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.