Article
Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells.
1994-10-01
Abstract excerpt
In this report, we show that the overexpression of tissue transglutaminase (tTG) in the human neuroblastoma cell line SK-N-BE(2) renders these neural crest-derived cells highly susceptible to death by apoptosis. Cells transfected with a full-length tTG cDNA, under the control of a constitutive promoter, show a drastic reduction in proliferative capacity paralleled by a large increase in cell death rate. The dying...
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Identifiers and source
- Literature Corpus work
- 7b2256cf-67eb-5cdf-80be-6e825f273d89
- DOI
- 10.1128/mcb.14.10.6584
