Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Introducing the Clusterin Gene Into Human Renal Cell Carcinoma Cells Enhances Their Metastatic Potential

1 May 2002

Abstract excerpt

PURPOSE: We recently reported a protective role of clusterin expression against apoptosis induced by a wide variety of stimuli in several human cancer models. In the current study we tested the hypothesis that clusterin over expression confers a benefit for the metastasis of renal cell carcinoma through the inhibition of apoptosis induced by the various obstacles the cancer cells may confront after detachment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caveolin-1 and cellular processes
Share to Clusterin in disease pathology
Share to GDF15 and Related Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11956479
DOI: 10.1016/s0022-5347(05)65129-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Introducing the Clusterin Gene Into Human Renal Cell Carcinoma Cells Enhances Their Metastatic PotentialPMID 11956479Read ↗

Introduction of clusterin gene into human renal cell carcinoma cells enhances their resistance to cytotoxic chemotherapy through inhibition of apoptosis both in vitro and in vivo.Semantic proximity Read ↗

Differential regulation of the clusterin gene by Ha-ras and c-myc oncogenes and during apoptosis.Semantic proximity Read ↗

RNA interference suppression of A100A4 reduces the growth and metastatic phenotype of human renal cancer cells via NF-kB-dependent MMP-2 and bcl-2 pathway.Semantic proximity Read ↗

The transmembrane domain of CEACAM1-4S is a determinant of anchorage independent growth and tumorigenicity.Semantic proximity Read ↗

Characterization of the invasive and metastatic phenotype in human renal cell carcinoma.Semantic proximity Read ↗

Antisense oligodeoxynucleotide therapy targeting clusterin gene for prostate cancer: Vancouver experience from discovery to clinicSemantic proximity Read ↗

Anoikis disruption of focal adhesion-Akt signaling impairs renal cell carcinoma.Semantic proximity Read ↗

VHL induces renal cell differentiation and growth arrest through integration of cell-cell and cell-extracellular matrix signaling.Semantic proximity Read ↗

Down-regulation of death-associated protein kinase-2 is required for beta-catenin-induced anoikis resistance of malignant epithelial cells.Semantic proximity Read ↗

Selection of adenoid cystic carcinoma cell clone highly metastatic to the lung: an experimental studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.