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Article

Co-receptor usage of HIV-1 primary isolates, viral burden, and CCR5 genotype in mother-to-child HIV-1 transmission.

AIDS (London, England) - 18 Aug 2000

Ometto L, Zanchetta M, Mainardi M, De Salvo G L, Garcia-Rodriguez M C, Gray L, Newell M L, Chieco-Bianchi L, De Rossi A

Abstract excerpt

OBJECTIVE: To investigate the relationship between CC chemokine receptor 5 (CCR5) genotype, viral load and co-receptor usage of maternal HIV-1 isolates in perinatal HIV-1 transmission. PATIENTS AND METHODS: A total of 181 mothers and infants were studied at the time of delivery. Wild-type (wt) and delta32 CCR5 alleles were determined by means of polymerase chain reaction (PCR). The viral load in maternal plasma...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Infectious Disease Transmission, Vertical

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Share to Pregnancy Complications, Infectious

Share to Receptors, CCR5

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Source

Identifiers

PMID: 10985308
DOI: 10.1097/00002030-200008180-00006

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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