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Article

Impaired binding of a DQ2 and DQ8-binding HSV VP16 peptide to a DQA10501/DQB10302 trans class II heterodimer.

Tissue antigens - 1 Jan 1999

Reichstetter S, Kwok W W, Nepom G T

Abstract excerpt

DQalpha and DQbeta trans heterodimeric HLA-DQ molecules form in individuals heterozygous for the DQ2 and DQ8 specificities. Unique functions and disease associations have been postulated for such trans-dimers, which may be different from cis-encoded DQ molecules encoded by the corresponding haplotypes. We analyzed the ability of the trans-dimer encoded by HLA-DQA1*0501/DQB1*0302 to bind a peptide antigen which...

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Share to Cell Line, Transformed
Share to Genes, MHC Class II
Share to Herpes Simplex Virus Protein Vmw65

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Herpesvirus 4, Human

Share to HLA-DQ alpha-Chains

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Source

Identifiers

PMID: 10082436
DOI: 10.1034/j.1399-0039.1999.530111.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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