Article
Donor-specific antibody to trans-encoded donor HLA-DQ heterodimer.
Human immunology - 1 Aug 2015
Habig Dennis F, Gaspari Justine L, Lokhandwala Parvez M, Domen Ronald E, Abendroth Catherine S, Kadry Zakiyah, Ghahramani Nasrollah, Shah Riaz Ali, Jain Ashokkumar, Shike Hiroko
Abstract excerpt
The majority of de novo donor specific HLA antibodies (DSAs) in transplant patients are directed to HLA-DQ antigens, which consist of a heterodimer of alpha and beta chains. Although a heterodimer can theoretically be cis- or trans-encoded, the sensitizing forms generally appear to be forms. DSA to DQ trans-heterodimer has never been reported. We reviewed 360 post-kidney transplant recipients (transplant:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.