Article
Distribution of the HIV resistance CCR5-Delta32 allele among Egyptians and Syrians.
Mutation research - 1 Mar 2007
Salem Abdel-Halim, Batzer Mark A
Abstract excerpt
A mutant allele of the beta-chemokine receptor gene CCR5 bearing a 32-basepair (bp) deletion that prevents cell invasion by the primary transmitting strain of HIV-1 has recently been characterized. Individuals homozygous for the mutation are resistant to infection, even after repeated high-risk exposure, but this resistance appears not absolute, as isolated cases of HIV-positive deletion homozygotes are emerging....
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