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Article

Identification of the gene variations in human CD22.

Immunogenetics - 1 Apr 1999

Hatta Y, Tsuchiya N, Matsushita M, Shiota M, Hagiwara K, Tokunaga K

Abstract excerpt

CD22, a member of the immunoglobulin superfamily, is a B-cell transmembrane glycoprotein that acts as an accessory-signaling component of the B-cell antigen receptor (BCR). Recent evidence indicating the role of CD22 as a negative regulator of BCR signal transduction prompted us to test the possibility that genetic variations of human CD22 may be associated with autoimmune diseases. In this study, variation...

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PMID: 10079291
DOI: 10.1007/s002510050494

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BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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