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Article

Screening of Variations in CD22 Gene in Children with B-Precursor Acute Lymphoblastic Leukemia.

Genetic testing and molecular biomarkers - 1 Sept 2016

Aslar Oner Deniz, Akin Dilara Fatma, Sipahi Kadir, Mumcuoglu Mine, Ezer Ustun, Kürekci A Emin, Akar Nejat

Abstract excerpt

BACKGROUND: CD22 is expressed on the surface of B-cell lineage cells from the early progenitor stage of pro-B cell until terminal differentiation to mature B cells. It plays a role in signal transduction and as a regulator of B-cell receptor signaling in B-cell development. OBJECTIVES: We aimed to screen exons 9-14 of the CD22 gene, which is a mutational hot spot region in B-precursor acute lymphoblastic leukemia...

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Identifiers

PMID: 27486888
DOI: 10.1089/gtmb.2016.0006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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